“Unparalleled” Anti -Snakes made from a bitten man 200 times

Scientists say that the blood of the United States, which deliberately injected itself in the name of the snake for nearly two decades, led to “unparalleled anti -“, as scientists say.

It has been shown that the antibodies in the blood of Tim Freddy protect from the deadly doses of a wide range of species in animal tests.

Current treatments should coincide with the specified types of toxic snakes to anyone.

But the mission of Mr. Freddy, which lasted 18 years, can be an important step in finding a global counter against all kinds of snake – that kills up to 140,000 people per year and leaves three times what many people need or face a permanent disability.

In total, Mr. Freddy holds more than 200 bites and more than 700 injections of the poison that he prepared from some of the most snakes in the world, including multiple types of MAMBAS, Cobras, Taipans and Kraits.

He initially wanted to build immunity to protect himself when dealing with snakes, and documenting his exploits on YouTube.

But the former truck mechanic said it was “completely tightened” early when two cobra bites left it in a quick sequence in a coma.

“I didn’t want to die. I didn’t want to lose a finger. I didn’t want to miss the work,” he told the BBC.

Mr. Freddy’s motivation was to develop better treatments for the rest of the world, explaining: “It has become just a lifestyle and continued to pay, pay and pay as much as possible – for people who are 8,000 miles away from me who die from Snakebite.”

Antivenom is currently made by injecting small doses of snake in animals, such as horses. It fights the immune system in poison by producing antibodies and is harvested for use as a treatment.

But the poison and the scapent must be closely compatible because the toxins in a toxic bite differ from one type to another.

There is a wide range inside the same species – anti -snakes in India Less Against the same type in Sri Lanka.

A team of researchers began searching for a type of immune defense called widespread antibodies. Instead of targeting a portion of the poison that makes it unique, it targets the common parts in whole categories of poison.

And that when Dr. Jacob Galanville, CEO Centivax, coincided with Tim Freddy.

He said: “Immediately I was like” if anyone in the world developed these antibodies on a large scale, it will be, so I have continued. “

“The first call, I was like” this may be embarrassing, but I would like to put my hands on some of your blood. “

Mr. Freddy agreed and the work was granted moral approval because the study will only take blood, instead of giving him more poison.

The search focused on Elapids – one of two toxic snakes – such as coral snakes, mambas, cobras, Taipans and Kraits.

Elapids primarily use nerve toxins in their poison, whose victims are paralyzed when the muscles needed to breathe.

The researchers chose 19 Elapids that the World Health Organization has been among the most bloody snakes on this planet. Then they started to roam Mr. Freddy’s blood for preventive defenses.

Their work, Detailed in the magazine cellSelect two widespread antibodies that can target two nerve toxins. And they added in a medication targeting a third to make a counter -cocktail.

In the experiments of mice, the cocktail meant that animals survived doses of 13 out of 19 types of toxic snakes. They had partial protection against the remaining six.

This is an “unparalleled breadth” of “unparalleled protection”, according to Dr. Glenville, who said that “it is likely to cover a full set of Elapids that are not current anti -anti -anti -aids.”

The team tries to improve antibodies and see if adding a fourth component can lead to complete protection against Elapid.

The other category of snake – the snake – depends more on blood toxins, which attack the blood, rather than nerve toxins. In total there are about ten wide categories of poison in snake venom, which also include cellular toxins that kill cells directly.

“I think we have in the next ten or fifteen years something effective against all seasons of Toxin,” said Professor Peter Coong, a researcher at the University of Colombia.

Hunting continues inside the blood of Mr. Farid.

Professor Coong said: “The TIM antibodies are really unusual – he taught his immune system to obtain this very wide recognition,” said Professor Coong.

The final hope is that you have either one antibiotic that can do everything, or one injection of albids and one defense.

Professor Nick Caswell, head of the Snake Research and Intervention Center at the Liverpool School of Equity Medicine, said that the extent of the reported protection was “definitely” and “strong evidence” that this was a possible approach.

“There is no doubt that this work moves the field forward in an exciting direction.”

But he warned that there was “a lot of work to do it” and that the antagonist still needed a wide -ranging test before using it in people.

But for Mr. Freddy, reaching this stage “makes me feel good.”

“I am doing something good for humanity and that was very important to me. I’m proud of that. It is great.”