Krisper can stop the spread of malaria by liberating one gene in mosquitoes

Crispr genetics remedy showed Great potential To treat diseases and even treat them, but scientists now discover how they can be used to prevent them as well. A team of researchers I found a way To free one gene in the mosquitoes that prevented him from moving malaria, according to a paper published in nature. Ultimately, these genetically modified mosquitoes can be launched in the wild, which helps to prevent some 600,000 malaria deaths that occur every year.

The mosquitoes affect up to 263 million people annually with malaria and efforts to reduce its population late. This is because both mosquitoes and their parasites that spread malaria have developed resistance to pesticides and other medicines.

Now, biologists from the University of California in San Diego, Jones Hopkins University and the University of California University in Berkeley have discovered a way to stop the transmission of malaria by changing one amino acid in mosquitoes. Changing mosquitoes still bitten people with malaria and pick up parasites from their blood, but it can no longer spread to others.

The Crispr-LAS9 system uses unwanted amino acid cut (alleles) that transports malaria and replaces it with a benign version. The unwanted allele, called L224, helps parasites swim to the salivary glands of mosquitoes where they can then injure a person. The new amino acid, Q224, prevents separate parasites from reaching the salivary glands, preventing infection in people or animals.

“With one accurate tablet, we (consisting of mosquito genes) turned into a strong shield that blocks the types of multiple malaria parasites and is likely to be through various types of mosquitoes and population, which paves the way for adaptable strategies in the real world to control this disease,” said researcher George Demopoulius of Johns Hopkins University.

Unlike previous methods of controlling malaria, changing this main gene does not affect health capabilities or reproduction of mosquitoes. This allowed researchers to create a technique for mosquitoes for the Q224 Allel Allel Allers and spread it through their residents to stop the transmission of malaria parasites in its paths. “We have harnessed the genetic tools of nature to convert mosquitoes into allies against malaria,” Dimopoulos said.

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