Even after decades of looking at cells, biologists still find surprises.
In the development, researchers at the University of Virginia and National Health Institutes revealed a new member called Hemifusome. This small structure associated with membrane works as a cell recycling center and may carry a key to treating many genetic diseases. The research has been published in Nature Communications.
“This is like the discovery of a new recycling center inside the cell,” said co -author Siham Ibrahim, the biologist at the University of Virginia, in a statement. “We believe that Hemifusome helps to manage how to pack cells and material operations, and when this process is going, it may contribute to diseases that affect many systems in the body.”
Scientists have not previously specified the temple because it only appears when needed. But thanks to the electron tomography-a technique of imaging that freezes cells and captures it in three-dimensional accuracy and in the accuracy near the atomic-the researchers were able to monitor the x-structure.
The researchers say the he inherents may help the formation of cellular vesicles, and small bags that move and combine materials throughout the cell. The study indicates that it may also help in forming other members of multiple vesicles. However, some evidence shows that the blood does not participate in nephritis, which is the traditional pathway in which the cells swallow an external substance.
“You can think of vesicles like small delivery trucks inside the cell,” Ibrahim said in a statement. “Hemifusome is similar to the loading berth where they call and transport the goods. It is a step in the process that we did not know exist.”
Despite their transit nature, hemoposos are not rare. It seems amazingly common in certain parts of the cells, especially near the cell membrane.
However, scientists are not completely sure of how or why hemoposomes are formed and then disappeared. They hope to discover this – as well as understand what is happening when Hemifusomes fails to work properly. Problems with how cells are dealing with goods in the root of many genetic disorders.
“This is just the beginning,” Ibrahim said in a statement. “Now that we have known the presence of blood, we can start asking how to behave in healthy cells and what happens when things get worse. This may lead to new strategies to treat complex genetic diseases.”
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