A look back at her funniest talk show appearances

When Hollywood lost Diane Keaton On October 11, 2025, it wasn’t just the end of an era. It was a reminder of how much laughter, chaos and charisma she brought to every room she entered. So, The Blast decided to dig back into some of Keaton’s most memorable talk show appearances, including those funny and unexpected moments that made her one of late night TV’s most beloved guests. From drinking chilled wine and cracking up Ellen DeGeneres To flirt her way through “Jimmy Kimmel Live!” After an exit that no one expected, Keaton’s frank humor and charm proved that she was as attractive off screen as she was on. Below, The Blast revisits Diane Keaton’s funniest, daring, and messiest talk show moments that still make us laugh and remind us exactly why she will always be one of Hollywood’s most authentic voices.

If anyone can turn “The Ellen DeGeneres Show” into a happy hour, it’s Keaton. During the December 3, 2020 episode, the Oscar winner once again proved that she was a walking mood board for unfiltered joy, quirky charm, and top-notch comedy.

Sitting comfortably on Ellen’s couch, complete with her wide-brimmed hat and oversized belt, Keaton immediately focused on her favorite part of the show. “You know what I love about this show? Wine,” she announced proudly. “Most people don’t offer me wine. But when I do participate, Ellen is very gracious about it.”

The moment Ellen handed her a glass of cold red, Keaton lit up, complimenting the host for using what she called “liquor store ice.” She swirled it dramatically, tasting the cold before taking a generous sip. “That’s the stuff,” she joked, flashing Keaton’s unmistakable smile.

When Ellen pointed out that some of her virtual audience were also enjoying wine from home, Keaton’s focus immediately, and predictably, shifted to the men. “You know, I’ve been holed up in the house alone,” she joked, looking at the screen. “I could use a guy or two.”

Elaine quickly interjected, laughing but the moderator said, “No, no, you won’t be funny now. Just keep drinking the wine.”

When it came to late-night television, Keaton was unpredictable, unfiltered, and always ready to blur the line between object and reality. Her appearance on “Jimmy Kimmel Live!” She was proof that no one could command a stage quite like her.

One of her most famous appearances turned into what fans now call an “audible walkout around Hollywood.” What started out as a light-hearted interview suddenly took a left turn when Kimmel pressed hard on his jokes, and Keaton, never the type to smile, simply got up and left.

The clip, which has been shared on YouTube countless times, shows Keaton getting up mid-conversation, adjusting her signature jacket, and saying, “I think I’ve said enough,” before heading backstage. Even as the audience gasped and Kimmel laughed awkwardly, Keaton’s exit made it clear she played by her own rules.

During another memorable “Jimmy Kimmel Live!” Keaton decided to show how she likes to be kissed. With playful confidence, she grabbed Kimmel by the tie and bent down to show him exactly how it’s done, then joked with him about being “so tough” compared to her “Book Club” co-star Andy Garcia. The crowd howled, Kimmel blushed, and Keaton sipped her drink as if nothing had happened.

Only Keaton could turn “The Tonight Show” into a frat party and make it somehow elegant. During one of her funniest late-night appearances, the Oscar-winning actress joined in Jimmy Fallon For a casual game of beer pong, although the glasses were filled with wine, as expected.

She admitted that she had never played before, and it showed. Her first throw was aggressive and went wide, and when Fallon took his turn, Keaton caught his ball in the air as if it were part of the game. Without missing a beat, she shrugged, laughed, and took a celebratory sip of wine anyway. Fallon completely lost his temper, and his laughter doubled as the audience joined in.