The Nobel Prize in the medicine granted for the inhabitants of the immune system

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Marie E Branko, Farid Ramsdale, and Sacon Sakajui won the Nobel Prize in Medicine, for discoveries on organizing the human immune system, which enhances the search for new treatments for cancer and other diseases.

The Nobel Association said on Monday that the three scientists will participate in SKR11MN ($ 1.17 million) for their work on what prevents immune cells from attacking the body.

The winners are part of the broader endeavor to investigate the complexities of the mechanisms of defending human diseases, harnessing them to fight microbes and understanding the reason for attacking the tissues of the body and cells in the so -called autoimmune conditions.

“Their discoveries were crucial to our understanding of how the immune system works, and why not all develop serious autoimmune diseases,” said Ully Cam, Chairman of the Nobel Nobel Prize 116 in physiology or medicine.

The trio is honored for their distinguished work, how the immune system decides what attacks it and what it leaves alone. They have identified the role of organizational T cells, which act as security guards to prevent immune cells from damaging the body.

The Nobel Committee said that Sakajuchi was “swimming against the tide” when he achieved the first big boom in 1995. Many researchers believed that the immune cells that are likely to be harmful to the body had been disposed of in a organ of the upper chest called the thymus gland. But Sakajui showed the existence of an unknown type of cells that helped stop autoimmune conditions.

The committee said that Branko and Amsdel continued this with another decisive discovery in 2001. They discovered that a boom in a gene known as Foxp3 made mice especially vulnerable to autoimmune conditions – and found the same thing in the equivalent human genetic code.

Then Sakagucci showed how Jin Foxp3 dominated the development of the cells he identified in 1995 – by now the name of the organizational T cells.

Yuko Hamzaki, a professor at the IPS research and application center at Kyoto University, said the award was a “great news” for “pioneering work” for Sakaguy.

Sakaguchi is a distinguished professor at the University of Osaka in Japan. BRUNKOW is a great program manager at the Systems Biology Institute in Seattle, while RamsDell is a scientific advisor at Sonoma Biother Assions.

Campi said that their discoveries launched investigations into various diseases, with promising early results for some cases, including dermatitis.

The other potential river included the suppression of autoimmune disorders and combating other conditions that are difficult to capture.

Sandberg said: “Perhaps (can) make organ transplants less problem by reducing the ability of the immune system to attack the new member,” Sandberg said. “Also, in cancers, it is explored if one can remove his repressive (immune) capacity, to facilitate immune cells to attack cancer cells.”

the Nobel Awards In physics, chemistry, literature, peace and the economy, they will all be revealed next week.



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