Scientists made human eggs from the skin cells and used it to form embryos

“The biggest challenge is how to make this egg transports half of the chromosomes – and the right half,” says Amato. “We are not there yet.” The team called “Mitomiosis” and tries to understand a better understanding of how to love chromosomes and how they are separated in order to find a way to experimentally urge these circumstances.

The ability to make eggs and sperm in the laboratory – called In the formation of walking in the laboratory, or IVGIt has been an increasing field of research in recent years.

In 2016, a group of Japanese researchers, led by Katsuko Hishi, reported that they are Playing the health mouse produced After making the entire mouse eggs in the laboratory dish. Later, they produced mouse eggs using male cells and as a result, they created puppies with two parents. These developments were achieved by re -programming skin cells from adult mice to stem cells, then increasing their persuasion to develop into eggs and war animals.

Metinori Saito at Kyoto University first documented in 2018 how his team Human blood cells have turned into stem cellsThen they turned into human eggs, but they were very immature so that they could not be fertilized to make embryos.

BIOSCINCES in the United States for Manufacturing, Avy Natal, Gameto, and Ovelle Bio are making eggs or sperm in the laboratory.

But the possibility raises great moral questions about how to use technology. in 2017 editorialBiological ethics warned that IVG may “raise the ghost of” fetal cultivation “on an incomplete scale. It is imagined, anyone of any age can be allowed to have a child. And collect with Apply for a fetus examinationIVG fertility clinics can be used to make large numbers of fetuses and then choose those with the most desirable characteristics. Genetics editing with IVG can also be used to eliminate pre -disease DNA or create new features.

Amato says it is likely to take another decade of research before IVG is considered safe or effective enough to test in people. Even so, it is not clear whether this technology will be allowed in the United States, because the Congress contestant prevents the food and drug administration from looking at clinical trials that involve genetically manipulating the fetus for the purpose of creating a child.

“Their method is very sophisticated and is well organized,” says Hayashi, a professor at the University of Osaka,. However, due to the high rate of chromosomal errors, “it is very ineffective and high risk to apply it immediately to the clinical application.”

Also, since their process requires donor eggs, it may limit its use as infertility. Since artificial insemination becomes more popular, the demand for donor eggs is increasing, and the use of waiting times can be used.

Amander Clark, the wandering scientist and biology in stem cells at the University of California, Los Angeles who did not participate in the work, agrees that in its current form, orsteal poisoning is not ready to use it in fertility care. But in the meantime, the search has other uses.

Clark says: “The technique of artistic sclerosis is an important artistic innovation and can be of high value for our understanding of the biology of difference in human eggs. Selective errors increase with the progress of women. Therefore, understanding the causes of selective errors is a critical field of research.”