Going to space can make your Gulf a lifetime

Faceflight pushes the human body to its borders, exposes astronauts to small gravity, high levels of radiation, and extended isolation periods. These pressures affect their health in different ways, and many of them are still fully understood. But if we want to go boldly as no person went before, we need to know all the risks before we take the jump.

And now a new research was published on Thursday, September 4 in the magazine The cell stem cell Provides evidence on another aspect of health in space. The researchers have discovered that the astronomy can accelerate the molecular aging of the stem cells in the blood, especially the stem cells that make up blood and human ancestors (HSPCs). These cells play a decisive role in the health of the immune system and the immune system, as it works as a basis for all different blood cells in the body. The results indicate that HSPCs loses some of its ability to regenerate and make new healthy cells after the space straightener.

A co -author of the Sanford Institute of Stem Cells and Professor of Medicine at the Faculty of Medicine at the University of California at the University of California, at the company A. press release.

Track cellular transformations in space

NASA was working hard to understand the space that the body is doing for years. the Teacher twin study For example, the involvement of Scott Kelly and (Senator now) showed Mark Kelly Changes in genetic expressionThe length of the telomere, and the intestinal microbium. But few studies have been discussed in how the maximum space affects the HSPCS levels, according to Jameson and its colleagues.

They have sought to fill this gap by looking at how these cells changed during and after a journey to space. Through partnership with NASA and Space Tango, a company that facilitates research and manufacturing in microscopic gravity, researchers have developed the “Nanoy Reactor” platform consisting of miniature 3D sensor systems. These new tools save human stem cells in space and monitor them using the imaging in which artificial intelligence works. The team sent its system to the International Space Station through the task of re -supplying Spacex.

Microscopic changes, major health effects

At least 32 years and up to 45 days of Faceflight, HSPCS showed clear signs of aging. For one, the cells have become more active than model, as they burn quickly through their energy reserves and the loss of their ability to rest and recover. This hindered their ability to renew over time. Their ability to make new and healthy cells also decreased, and they showed signs of DNA damage, the shortcuts, and infections inside the mitochondria. They even activated hidden sections of their genome, which usually remain asleep as it appears to be a desperate attempt to maintain stability.

These changes can weaken immune function, in turn increases the risk of disease, according to researchers. It is worth noting that only some reverse damage when the cells were placed in an area other than space. This indicates that it may be possible to recover the late HSPCs after space flight, but there may be limits.

Because humans aim to travel far from our original planet than ever, and understand The health risks associated with the distance of space in the long term It has become increasingly important. Jamieson and its colleagues plan to dive deeper into cellular effects with the additional missions of ISS and studies based on the astronaut. She said: “This is an essential knowledge as we enter a new era of traveling to the commercial space and searching for the low Earth’s orbit,” she said.