Initially, scientists pick up the transplantation of the human fetus in the actual time

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A team of scientists has just got a peek on one of the first and most basic steps to create a human life. Today’s research highlights how they captured – for the first time – to properly plant the human fetus during its occurrence.

Researchers at the Biological Engineering Institute in Catalonia (IBEC), in cooperation with the University of Dixius Hospital, detailing their work in studying Published Friday in scientific progress. Among other things, shots show that human embryos use strength to wander around the uterus to plant. The researchers say that the new method may allow scientists to understand the reason for the failure of the embryos often in transplantation, and one day improves fertility treatment.

“The reason we want to start studying the planting is that the transplant is the main road barrier in human reproduction,” said the author of the study, Samuel Oujngerus, the main researcher in the IBEC biological engineering group, for Gizmodo. “But we know very little about it and we know very little because it happens inside the mother.”

Scientists have definitely learned a lot over time on how the human fetus developed. But there were restrictions on this research, Ojosnegros notes. We only managed to study the first few days of the human fetus in the actual time, before planting. Next, most research is looking at footage of the fetus’s development, and it is usually taken from other non -human animals. These animal models are an important tool, but they can only tell us how people develop in the womb. The planting is the first step of pregnancy, and only after the fetus is included in the uterus that the pregnancy has already begun.

The team, led by scientists Amili Judo and Anna Seriola, created a substance that could mimic the external tissue that the fetus hangs to plant. This gel -like matrix is often made of collagen, but is also full of other important proteins for the development of the fetus. With their creation at hand, they are now able to record a microscope how the human fetus itself is grown. They also studied mouse embryos for comparison and noticed some important differences.

Human fetus + invasion. mp4
Team footage of a human fetus. The first half shows the cell pressure in the fetus. The second half shows the fetus invading the artificial uterus matrix. © Catalonia Biomatic Institute (IBEC)

“If you put it on the matrix, it remains superficially, spreads, but it will not invade. It will spread mainly superficially. While a person, if you put it on the surface, it will dig a hole, penetrate, and will bury himself inside and then grow,” explained Ojosnegros. “So, the human fetus is stronger, it is greater, and it is a more tweeting way.”

There are many other remaining puzzles that are resolved around the transplant, including the exact mechanisms that the fetus uses to invade the uterus strongly. But the lessons that Ojosnegros can learn and other scientists from this work can help families in the future. The researchers only notice this 30 % of the embryos (Whether from normal childbirth or fertilization in the laboratory), it makes it along the way to the birth, and those who are not lost during the transplant or immediately after. So just the ability to see how the process is revealed can provide vital evidence about how to prevent miscarriage or improve fertility.

Researchers are planning to continue studying the privacy and generalities of the fetal transplantation, but they also hope to unify the materials used in this research so that others can conduct their similar experiences. Ojosnegros also wants to highlight the contributions of Dexeus University Hospital and patients who have made the donation embryos this work possible in the first place.

“I think it is good to realize that without the generosity of patients who donated the research fetus, we were unable to study our own types,” he said.



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